A successful physician and devoted family man, John Dolittle (Murphy) seems to have the world by the tail, until a long-suppressed talent he possessed as a child - the ability to communicate with animals - is suddenly reawakened...with a vengeance! Now every creature within squawking distance wants the good doctor's advice, unleashing an outrageous chain of events that turns his world upside down! Featuring an all-star menagerie of voice talent (including Chris Rock, John Leguizamo, Norm MacDonald, Albert Brooks, Garry Shandling and Ellen DeGeneres), this wild and wooly free-for-all is your prescription for hilarious hijinks and "mischievous fun!" (The New York Times).